OSMRβ, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityOSMRβ, Human
CloneREA837
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatbiotin conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionOSMRβ Antibody, anti-human, Biotin, REAfinity™. Clone REA837 recognizes the human Anti-OSMRβ antigen, the β subunit of the Oncostatin-M-specific receptor (OSMR). OSMRβ belongs to the IL-6 receptor family and is activated by Oncostatin-M. Its expression is up-regulated by IFN-γ and bacterial lipopolysaccharides (LPS). OSMRβ is found in high levels in all neural cells as well as in fibroblast, in epithelial cells, and in a variety of tumor cell lines. OSM is most closely related to leukemia inhibitory factor (LIF) and it utilizes the LIF receptor in addition to its specific receptor in the human. | Additional information: Clone REA837 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesOSMRb, IL-31RB
Gene, Accession #Gene ID: 9180
Catalog #130-112-927
Price$93
Order / More InfoOSMRβ, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesMosley, B. et al. (1996) Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation. J. Biol. Chem. 271 (51): 32635-32643. | Tanaka, M. and Miyajima, A. (2003) Oncostatin M, a multifunctional cytokine. Rev. Physiol. Biochem. Pharmacol. 149: 39-52.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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