CD218a (IL-18Rα), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD218a (IL-18Rα), Mouse |
| Clone | REA947 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD218a (IL-18Rα) Antibody, anti-mouse, PE, REAfinity™. Clone REA947 recognizes the mouse CD218a antigen, also known as interleukin-18 receptor alpha (IL-18Rα). CD218a, a member of the immunoglobulin superfamily, is a subunit of the heterodimeric receptor complex of alpha- and beta-chains for the pleiotropic proinflammatory IL-18 cytokine. IL-18 belongs to the IL-1 superfamily and is expressed by monocytes, macrophages, epithelial cells, and keratinocytes. CD218a (IL-18Rα) is found on T?1 cells, subsets of NK cells, and granulocytes. IL-18 plays a role in induction of inflammatory mediators, regulation of the cytotoxic activity of NK and T cells, and differentiation and activation of T?1 and T?2 cells. | Additional information: Clone REA947 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | IL-18Ra, IL-18Rα, IL-18R1, IL-18R-1, IL-1Rrp |
| Gene, Accession # | Gene ID: 16182 |
| Catalog # | 130-115-676 |
| Price | $222 |
| Order / More Info | CD218a (IL-18Rα), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Wu, C. et al. (2003) IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction. J Immunol 170 (11): 5571-5577. | Sergi, B. et al. (2004) Interleukin 18 receptor. J. Biol. Regul. Homeost. Agents 18 (1): 55-61. | Huang, H. Y. et al. (2010) Eutopic endometrial interleukin-18 system mRNA and protein expression at the level of endometrial-myometrial interface in adenomyosis patients. Fertil. Steril. 94 (1): 33-39. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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