Slan (M-DC8), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificitySlan (M-DC8), Human
CloneDD-1
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgMκ
Formatallophycocyanin (APC) conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsFlow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
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DescriptionSlan (M-DC8) Antibody, anti-human, APC. The Anti-Slan (M-DC8) antibody (clone DD-1) recognizes 6-Sulfo LacNAc (Slan), which is a carbohydrate modification of P-selectin glycoprotein ligand-1 (PSGL-1). This antigen is characteristically expressed on a new subset of peripheral blood mononuclear cells (PBMCs) with features closely related to CD16+CD14low monocytes. | Slan (M-DC8)+ cells constitute 0.5-2% of all PBMCs with similar frequencies among mononuclear cells from cord blood.
Immunogenn/a
Other NamesSELPLG, CD162, CLA, PSGL-1, PSGL1
Gene, Accession #n/a
Catalog #130-119-951
Price$140
Order / More InfoSlan (M-DC8), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesSchakel, K. et al. (2002) 6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells. Immunity 17: 289-301. | de Baey, A. et al. (2001) Phenotype and function of human dendritic cells derived from M-DC8+ monocytes. Eur. J. Immunol. 31: 1646-1655. | Schakel, K. et al. (1998) A novel dendritic cell population in human blood: one-step immunomagnetic isolation by a specific mAb (M-DC8) and in vitro priming of cytotoxic T lymphocytes. Eur. J. Immunol. 28: 4084-4093.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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