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Antigenic Specificity | α-Tubulin, Human/Mouse/Rat |
Clone | REAL582 |
Host Species | Recombinant Human |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 200 µL |
Concentration | n/a |
Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | α-Tubulin Antibody, anti-human/mouse/rat, FITC, REAdye_lease™. Clone REAL582 is an antibody fragment derived from the full α-Tubulin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL582 recognizes the human, mouse and rat alpha chain of Tubulin (α-Tubulin), a heterodimer conisting of homologous but not identical a and b tubulin subunits. Tubulin is a member of the tubulin superfamily, which consists of six members (a, b, g, d, e and z tubulins) Tubulin is expressed by nearly all eukaryotic cells. Cancer cells show moderate to strong cytoplasmic expression, hepatocellular carcinomas have a weakly or negative expression. Tubulin is an essential part of microtubules, which are involved in a variety of cellular processes. They form the cytoskeleton and play a role in mitosis and meiosis. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
Immunogen | n/a |
Other Names | TUBA, α Tubulin |
Gene, Accession # | n/a |
Catalog # | 130-126-208 |
Price | $400 |
Order / More Info | α-Tubulin, Human/Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Nogales, E. et al. (1998) Structure of the alpha beta tubulin dimer by electron crystallography. Nature 391 (6663): 199-203. | Findeisen, P. et al. (2014) Six subgroups and extensive recent duplications characterize the evolution of the eukaryotic tubulin protein family. Genome Biol. Evol. 6 (9): 2274-2288. |