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Antigenic Specificity | PSMA, Human |
Clone | REA408 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PSMA Antibody, anti-human, APC, REAfinity™. Clone REA408 recognizes the human prostate-specific membrane antigen (PSMA) antigen, a single-pass type II membrane protein which is also known as folate hydrolase 1 (FOLH1), glutamate carboxypeptidase 2 (GCP2), or N-acetylated-alpha-linked acidic dipeptidase I (NAALADase). PSMA is a zinc metallopeptidase which catalyzes the hydrolysis of N-acetylaspartylglutamate to glutamate and N-acetylaspartate. It is expressed with low levels in the small intestine, renal tubular cells, and salivary gland, and is over-expressed in prostate cancer tissue. PSMA is also expressed in the nervous system. | Additional information: Clone REA408 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | FOLH1, FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSM, mGCP, NAALADase I |
Gene, Accession # | Gene ID: 2346 |
Catalog # | 130-117-790 |
Price | $140 |
Order / More Info | PSMA, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Israeli, R. S. et al. (1993) Molecular cloning of a complementary DNA encoding a prostate-specific membrane antigen. Cancer Res. 53 (2): 227-230. | Ghosh, A. et al. (2004) Tumor target prostate specific membrane antigen (PSMA) and its regulation in prostate cancer. J. Cell. Biochem. 91 (3): 528-539. | Luthi-Carter, R. et al. (1998) Molecular characterization of human brain N-acetylated alpha-linked acidic dipeptidase (NAALADase). J. Pharmacol. Exp. Ther. 286 (2): 1020-1025. |