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Antigenic Specificity | CD104 (Integrin β4), Human |
Clone | REA236 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | PE-Vio 770 conjugate |
Size | 100 tests in 1 mL |
Concentration | 1:11 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD104 (Integrin β4) Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA236 recognizes CD104, which is also known as integrin β4. Integrins are a family of type I transmembrane heterodimeric glycoprotein receptors and exist as non-covalently bound α and β subunits. CD104 interacts with α6 integrin and serves as receptor for laminin and component of hemidesmosomes. Expression of α6β4 integrin is found in the basal aspect of stratified epithelia such as epidermis, stratified squamous epithelium of squamous mucosa, urothelium, and certain tumor cells. | Additional information: Clone REA236 displays negligible binding to Fc receptors. | |
Immunogen | n/a |
Other Names | Itgb4 |
Gene, Accession # | Gene ID: 3691 |
Catalog # | 130-101-445 |
Price | $350 |
Order / More Info | CD104 (Integrin β4), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Simon-Assmann, P. et al. (1994) Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine. Dev. Dyn. 201 (1): 71-85. | Tuckwell, D. S. et al. (1993) Integrins: a review of their structure and mechanisms of ligand binding. Symp. Soc. Exp. Biol 47: 107-136. |