CD49b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD49b, Human |
| Clone | REA188 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | APC-Vio 770 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD49b Antibody, anti-human, APC-Vio® 770, REAfinity™. Clone REA188 recognizes CD49b, also known as integrin α2 chain. CD49b is single-pass, 150 KDa, type I membrane protein. Together with integrin β1 (CD29), CD49b forms the VLA-2 receptor, which binds ligands such as collagen, fibrinogen, and laminin and thus mediate the attachment of several cell types to extracellular matrix. Expression of CD49b is found on lymphocytes, activated T cells, monocytes, epithelial cells, and platelets. | Additional information: Clone REA188 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | Itga2, BR, α2 integrin, gpIa, HPA-5, VLA-2, VLAA2, CD49b, VLA-2α |
| Gene, Accession # | Gene ID: 3673 |
| Catalog # | 130-129-802 |
| Price | $400 |
| Order / More Info | CD49b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Elices, M. J. and Hemler, M. E. (1989) The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others. Proc. Natl. Acad. Sci. U.S.A. 86: 9906-9910. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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