CD8, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD8, Human |
| Clone | REA734 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD8 Antibody, anti-human, FITC, REAfinity™. Clone REA734 recognizes the human CD8 antigen, a cell-surface glycoprotein also known as Leu-2 or CD8a. CD8 is strongly expressed on human cytotoxic T cells and thymocytes as well as on a subset of natural killer (NK) cells. The CD8 antigen is a disulfide-linked dimer that exists either as a CD8a homodimer or as a CD8α/β heterodimer. CD8 acts as a coreceptor for the T cell receptor and binds to the MHC class I molecules. CD8 is involved in T cell development and activation of mature T cells. The CD8 antibody recognizes the α-subunit of the antigen. | Additional information: Clone REA734 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Leu-2, CD8a, MAL, p32, Cd8b1, LY3, Lyt3, P37, Ly-2 |
| Gene, Accession # | Gene ID: 925, 926 |
| Catalog # | 130-110-677 |
| Price | $264 |
| Order / More Info | CD8, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Devine, L. et al. (1999) Orientation of the Ig domains of CD8 alpha beta relative to MHC class I. J Immunol 162 (2): 846-851. | Gao, G. F. et al. (2000) Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor. Immunol. Today 21 (12): 630-636. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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