CD8b, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD8b, Rat |
| Clone | REA222 |
| Host Species | Recombinant Human |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD8b Antibody, anti-rat, FITC, REAfinity™. Clone REA222 recognizes rat CD8b, a member of the immunoglobulin superfamily also known as T cell surface glycoprotein Lyt-3. CD8b is expressed on cytotoxic T cells, thymocytes, and macrophages as a heterodimer with CD8a. CD8 identifies cytotoxic/suppressor T cells that interact with MHC class I bearing targets and plays a role in the process of T cell mediated killing. Flow cytometric analysis showed that CD8 T cells from lymph nodes or spleen of normal rats almost exclusively express the α/β heterodimer, regardless of the T cell receptor isotype. In contrast, natural killer cells carry only CD8a chains. | Additional information: Clone REA222 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | Cd8b1 |
| Gene, Accession # | Gene ID: 24931 |
| Catalog # | 130-103-321 |
| Price | $27 |
| Order / More Info | CD8b, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Torres-Nagel, N. et al. (1992) Differential thymus dependence of rat CD8 isoform expression. Eur. J. Immunol. 22 (11): 2841-2848. | Duplan, V. et al. (2007) Tracking antigen-specific CD8+ T cells in the rat using MHC class I multimers. J. Immunol. Methods 320 (1-2): 30-39. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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