CD107b, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD107b, Mouse |
| Clone | M3/84 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG1κ |
| Format | APC-Vio 770 conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD107b Antibody, anti-mouse, APC-Vio® 770. Clone M3/84 recognizes the mouse CD107b antigen, a highly glycosylated 110 kD Single-pass type I membrane protein also known as Lysosome-associated membrane protein-2 (LAMP-2) or Mac-3 antigen. It is widely located in lysosomal membranes and the plasma membrane of macrophages and some myeloid cell lines. Under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, in malignant carcinoma cells, and in cytotoxic T lymphocytes, it is also found at the cell surface. CD107b has been described as a receptor for the selective import and degradation of cytosolic proteins in the lysosome, or chaperone-mediated autophagy. |
| Immunogen | n/a |
| Other Names | LAMP-2, LGP-B, Lamp II, Mac3 |
| Gene, Accession # | Gene ID: 16784 |
| Catalog # | 130-106-366 |
| Price | $60 |
| Order / More Info | CD107b, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Tanaka, Y. et al. (2000) Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice. Nature 406 (6798): 902-906. | Cha, Y. et al. (1990) The cDNA sequence of mouse LAMP-2. Evidence for two classes of lysosomal membrane glycoproteins. J. Biol. Chem. 265 (9): 5008-5013. | Asaoka, Y. et al. (2013) Immunohistochemistry of LAMP-2 and adipophilin for phospholipidosis in liver and kidney in ketoconazole-treated mice. Exp. Toxicol. Pathol. 65 (6): 817-823. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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