CD38, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD38, Mouse |
| Clone | REA616 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD38 Antibody, anti-mouse, Biotin, REAfinity™. Clone REA616 recognizes the mouse CD38 antigen, a 42 kDa single-pass type II membrane protein, which is also known as ADP-ribosyl cyclase 1. CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis. In the mouse, CD38+ hematopoietic cells include B cells, subsets of T cells, monocytes, and macrophages. CD38 expression on these cells is modulated following activation and differentiation. In contrast to humans, CD38 expression is downregulated on mouse germinal center B cells and mouse mature plasma cells. | Additional information: Clone REA616 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, ADPRC 1, I-19, NIM-R5, T10 |
| Gene, Accession # | Gene ID: 12494 |
| Catalog # | 130-109-331 |
| Price | $30 |
| Order / More Info | CD38, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Oliver, A. M. et al. (1997) Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells. J Immunol 158 (3): 1108-1115. | Cockayne, D. A. et al. (1998) Mice deficient for the ecto-nicotinamide adenine dinucleotide glycohydrolase CD38 exhibit altered humoral immune responses. Blood 92 (4): 1324-1333. | Howard, M. et al. (1993) Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38. Science 262 (5136): 1056-1059. | Bean, A. G. et al. (1995) CD38 expression on mouse T cells: CD38 defines functionally distinct subsets of alpha beta TCR+CD4-CD8- thymocytes. Int. Immunol. 7 (2): 213-221. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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