CD49d, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-CD49d, Rat antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CD49d, Rat |
| Clone | MRα4-1 |
| Host Species | Rat |
| Reactive Species | rat |
| Isotype | IgG2aκ |
| Format | Vio Bright FITC conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD49d Antibody, anti-rat, Vio® Bright FITC. Clone MRα4-1 recognizes the mouse CD49d antigen, a 150 kDa integrin family member, also known as integrin α4 chain or VLA-4α chain. Integrins are cell-surface receptors, expressed as heterodimers essential in various processes mediating intercellular or cell-matrix interaction. CD49d associates non-covalently with the integrin β or β1 (CD29) forming the complex VLA-4, which is expressed on peripheral lymphocytes, thymocytes, eosinophils, basophils, mast cells, dendritic cells, and monocytes. VLA-4 plays a critical role in adhesion and migration of cells into tissues by binding to its ligand VCAM-1 (CD106). In T cells, on ligation of MAdCAM-1, α4β7 integrin also provides costimulation of T cell receptor/CD3-mediated signaling. |
| Immunogen | n/a |
| Other Names | ITGA4, α4 integrin chain, VLA-4α chain |
| Gene, Accession # | Gene ID: 311144 |
| Catalog # | 130-111-487 |
| Price | $187 |
| Order / More Info | CD49d, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Berlin, C. et al. (1993) Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell 74 (1): 185-195. | Fogler, W. E. et al. (1996) NK cell infiltration into lung, liver, and subcutaneous B16 melanoma is mediated by VCAM-1/VLA-4 interaction. J Immunol 156 (12): 4707-4714. | Tsuzuki, Y. et al. (1996) alpha 4 integrin plays a critical role in early stages of T lymphocyte migration in Peyer's patches of rats. Int. Immunol. 8 (3): 287-295. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies