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Antigenic Specificity | HLA-DR, Human |
Clone | REA805 |
Host Species | Recombinant Human |
Reactive Species | human, nonhuman primate |
Isotype | IgG1 |
Format | purified |
Size | 100 µg in 100 µL |
Concentration | n/a |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HLA-DR Antibody, anti-human, pure, REAfinity™. Clone REA805 recognizes the human major histocompatibility (MHC) class II antigen HLA-DR, a heterodimeric cell surface glycoprotein belonging to the Ig superfamiliy. HLA-DR is constitutively expressed on professional antigen-presenting cells like dendritic cells, B cells, and monocytes/macrophages. Its expression is further up-regulated upon activation. On T cells, natural killer (NK) cells, hematopoietic precursor cells, and some epithelial cells the expression of HLA-DR is induced by cell activation. | Additional information: Clone REA805 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
Gene, Accession # | Gene ID: 3123, 3122, 3127, 3126, 3125 |
Catalog # | 130-122-299 |
Price | $205 |
Order / More Info | HLA-DR, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Brodsky, F. M. (1984) A matrix approach to human class II histocompatibility antigens: reactions of four monoclonal antibodies with the products of nine haplotypes. Immunogenetics 19 (3): 179-194. | Edwards, J. A. et al. (1986) Differential expression of HLA class II antigens in fetal human spleen: relationship of HLA-DP, DQ, and DR to immunoglobulin expression. J Immunol 137 (2): 490-497. |