CD11a/CD18, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD11a/CD18, Mouse |
| Clone | REA880 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD11a/CD18 Antibody, anti-mouse, APC, REAfinity™. Clone REA 880 recognizes the CD11a/CD18 heterodimer, also known as lymphocyte function-associated antigen 1 (LFA-1). LFA-1 is a member of the integrin family and consists of two chains, a (CD11a) and b2 (CD18). It is expressed on T and B cells as well as on macrophages and neutrophils. LFA-1 plays an essential role in the immune system, e.g., in leukocyte adhesion by interaction with ICAM-1 and ICAM-2, in cytotoxic T cell-mediated killing, antibody-dependent killing by granulocytes and monocytes, and in T cell proliferation. | Additional information: Clone REA880 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | LFA-1 |
| Gene, Accession # | Gene ID: 16408, 16414 |
| Catalog # | 130-114-317 |
| Price | $365 |
| Order / More Info | CD11a/CD18, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Kaufmann, Y. et al. (1991) Cloning of the murine lymphocyte function-associated molecule-1 alpha-subunit and its expression in COS cells. J Immunol 147 (1): 369-374. | Lub, M. et al. (1995) Ins and outs of LFA-1. Immunol. Today 16 (10): 479-483. | Liu, Z. et al. (2006) Differential roles for beta2 integrins in experimental autoimmune bullous pemphigoid. Blood 107 (3): 1063-1069. | Liu, Y. et al. (2011) Expression of p16INK4a prevents cancer and promotes aging in lymphocytes. Blood 117: 3257-3267. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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