Cleaved PARP1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Cleaved PARP1, Human |
| Clone | REA1316 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cleaved PARP1 Antibody, anti-human, PE, REAfinity™. Clone REA1316 recognizes the human PARP1 enzyme, Poly (ADP-ribose) polymerase 1, that modifies various nuclear proteins by poly(ADP-ribosyl)ation. PARP1 plays a role in DNA repair in response to environmental stress, genomic stability, and programmed cell death. It catalyzes the transfer of ADP-ribose units from NAD+ to a variety of nuclear proteins including topoisomerases, histones, and PARP itself. PARP1 is involved in differentiation, proliferation and tumor transformation. Furthermore PARP can be cleaved by many ICE-like caspases, it is a cleavage- target of the caspase-3 protease activity associated with apoptosis. Cancer tissues express PARP1 to a high extent, including neuroblastoma, testicular and other germ cell tumors, malignant lymphoma and breast and colon cancer. | Additional information: Clone REA1316 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | ADPRT, PARP, PPOL, PARP-1, ARTD1 |
| Gene, Accession # | Gene ID: 142 |
| Catalog # | 130-128-159 |
| Price | $362 |
| Order / More Info | Cleaved PARP1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | n/a |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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