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Antigenic Specificity | CD58 (LFA-3), Human |
Clone | REA1098 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD58 (LFA-3) Antibody, anti-human, APC, REAfinity™. Clone REA1098 recognizes human CD58, a 45-70 kDa cell surface molecule which is a member of the immunoglobin superfamily. It is expressed on professional APCs (antigen-presenting cells) such as B cells, dendritic cells, macrophages, and epithelial cells as well as on T cells, monocytes, erythrocytes, endothelial cells, and fibroblasts. LFA-3 interacts with CD2 on T cells and is important for interaction between T cells and professional APCs. | Additional information: Clone REA1098 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | LFA-3, ag3 |
Gene, Accession # | Gene ID: 965 |
Catalog # | 130-118-735 |
Price | $142 |
Order / More Info | CD58 (LFA-3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Sanchez-Madrid, F. et al. (1982) Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U.S.A. 79: 7489-7493. | Dengler, T. J. et al. (1992) Structural and functional epitopes of the human adhesion receptor CD58 (LFA-3). Eur. J. Immunol. 22 (11): 2809-2817. | Wang, J. H. et al. (1999) Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors. Cell 97 (6): 791-803. |