GP2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | GP2, Human |
| Clone | REAL1315 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | allophycocyanin (APC) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | GP2 Antibody, anti-human, APC, REAdye_lease™. Clone REAL1315 is an antibody fragment derived from the full GP2 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1315 recognizes the GP2 transmembranprotein, associated with the zymogen granule membranes, also known as Glycoprotein 2 and ZAP75. GP2 functions as an intestinal M-cells transcytotic receptor specific of type-I-piliated bacteria that participates to the mucosal immune response toward these bacteria. Glycoprotein 2 is expressed on pancreatic zymogen granule membrane and also on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
| Immunogen | n/a |
| Other Names | Glycoprotein 2, ZAP75 |
| Gene, Accession # | n/a |
| Catalog # | 130-130-342 |
| Price | $511 |
| Order / More Info | GP2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Clive, K. S. et al. (2012) The GP2 peptide: a HER2/neu-based breast cancer vaccine. J Surg Oncol 105 (5): 452-458. | Somma, V. et al. (2013) The Novel Crohn's Disease Marker Anti-GP2 Antibody Is Associated with Ileocolonic Location of Disease.: 683824. | Lin, Y. et al. (2020) Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer. Nat Commun. 11 (1): 3175. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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