Desmin, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityDesmin, Human
CloneREA1134
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size200 µL
Concentration1:50
ApplicationsMICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
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DescriptionDesmin Antibody, anti-human, PE, REAfinity™. Clone REA1134 recognizes the human Desmin, a muscle-specific type III intermediate filament, which is found in cardiac muscle, skeletal muscle and smooth muscle tissue. Desmin is essential for proper muscular structure and function and plays an important role in regulating the sarcomere architecture and integrating sarcolemma, Z disk, and nuclear membrane in sarcomeres. | Clone REA1134 does not react with Keratin, Vimentin and Neurofilament and GFAP. | Additional information: Clone REA1134 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesDES
Gene, Accession #Gene ID: 1674
Catalog #130-119-490
Price$315
Order / More InfoDesmin, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesDebus, E. et al. (1983) Monoclonal antibodies to desmin, the muscle-specific intermediate filament protein. EMBO J. 2 (12): 2305-2312. | Altmannsberger, S. et al. (1985) Desmin is a specific marker for rhabdomyosarcomas of human and rat origin. Am. J. Pathol. 118 (1): 85-95. | Li, Z. et al. (1997) Desmin is essential for the tensile strength and integrity of myofibrils but not for myogenic commitment, differentiation, and fusion of skeletal muscle. J. Biol. Chem. 139 (1): 129-144.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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