CD41b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD41b, Human |
| Clone | REA336 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 tests in 300 µL |
| Concentration | 1:11 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD41b Antibody, anti-human, APC, REAfinity™. Clone REA336 recognizes the human CD41b antigen, the β chain of integrin α-IIb (CD41). CD41 associates with CD61 to form the heterodimeric GPIIb/GPIIIa complex that is present on human megakaryocytes and platelets. The CD41/CD61 complex is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin, as well as vitronectin and mediates platelets aggregation. | Additional information: Clone REA336 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | ITGA2B, BDPLT16, BDPLT2, GP2B |
| Gene, Accession # | Gene ID: 3674 |
| Catalog # | 130-105-072 |
| Price | $142 |
| Order / More Info | CD41b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Gekas, C. et al. (2013) CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood 121 (22): 4463-4472. | Poncz, M. et al. (1987) Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors. J. Biol. Chem. 262 (18): 8476-8482. | Corbel, C. et al. (2005) (alpha)IIb integrin, a novel marker for hemopoietic progenitor cells. Int. J. Dev. Biol. 49 (2-3): 279-284. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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