CD45, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD45, Mouse |
| Clone | REA737 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 2x 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD45 Antibody, anti-mouse, PE, REAfinity™. Clone REA737 recognizes the mouse CD45 antigen, also known as Ly-5 or leukocyte common antigen (LCA), which belongs to the protein tyrosine phosphatase (PTP) family. CD45 is a glycoprotein which is involved in T cell receptor and B cell receptor signal transduction. It is expressed at high levels on all cells of hematopoietic origin except for erythrocytes. Clone REA737 reacts with all CD45 isoforms. CD45 can be used to discriminate leukocytes from non-hematopoietic cells. | Additional information: Clone REA737 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | L-CA, LCA, Ly-5, T200 |
| Gene, Accession # | Gene ID: 19264 |
| Catalog # | 130-110-659 |
| Price | $475 |
| Order / More Info | CD45, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Pulido, R. et al. (1988) Comparative biochemical and tissue distribution study of four distinct CD45 antigen specificities. J Immunol 140 (11): 3851-3857. | Arendt, C. W. et al. (1997) Identification of the CD45-associated 116 kDa and 80 kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II. J. Biol. Chem. 272 (20): 13117-13125. | Trowbridge, I. S. et al. (1994) CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu. Rev. Immunol. 12: 85-116. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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