Jagged2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Jagged2, Human |
| Clone | REA1036 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PE-Vio 770 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Jagged2 Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA1036 recognizes the human Jagged2 protein, which is one of the several mammalian Notch ligands. Jagged2 is expressed by various organs and cell types and is involved in regulation of cell differentiation processes, such as lymphocyte development, myogenesis, and neurogenesis. Jagged2 is reported to be essential for the regulation of spermatogenesis. Jagged2 is also expressed on some lymphoma and leukemia cells and various other tumor cells and can be expressed by various antigen-presenting cells (APC) and may contribute to APC-directed peripheral T cell differentiation. | Additional information: Clone REA1036 displays negligible binding to Fc receptors |
| Immunogen | n/a |
| Other Names | JAG2, HJ2, SER2 |
| Gene, Accession # | Gene ID: 3714 |
| Catalog # | 130-117-448 |
| Price | $365 |
| Order / More Info | Jagged2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Luo, B. et al. (1997) Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor. Mol. Cell. Biol. 17 (10): 6057-6067. | Passos, G. S. et al. (2006) Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects. Schizophr. Res. 88 (1-3): 275-282. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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