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Antigenic Specificity | Synapsin-1, Human/Mouse |
Clone | REAL872 |
Host Species | Recombinant Human |
Reactive Species | human, mouse |
Isotype | n/a |
Format | phycoerythrin (PE) conjugate |
Size | 200 µL |
Concentration | n/a |
Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Synapsin-1 Antibody, anti-human/mouse, PE, REAdye_lease™. Clone REAL872 is an antibody fragment derived from the full Synapsin-1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL872 recognizes the human and mouse neuron- specific phoshoprotein Synapsin-1. Synapsins are substrates for different protein kinases and involved in the regulation of neurotransmitter release. Synapsin-1 occurs in two isoforms (Synapsin Ia and Synapsin Ib) and belongs to the most specific markers of synapses throughout the central and peripheral nervous system. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
Immunogen | n/a |
Other Names | Synapsin 1, Synapsin I, Syn1, SYN-1 |
Gene, Accession # | n/a |
Catalog # | 130-129-692 |
Price | $470 |
Order / More Info | Synapsin-1, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Huttner, W. B. et al. (1983) Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J. Cell Biol. 96 (5): 1374-1388. | Sudhof, T. C. et al. (1989) Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins. Science 245 (4925): 1474-1480. | Patzke, C. et al. (2019) Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell 179 (2): 498-513. |