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Antigenic Specificity | CD131, Mouse |
Clone | REA193 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 9 µg in 300 µL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD131 Antibody, anti-mouse, APC, REAfinity™. Clone REA193 recognizes CD131, the IL-3 receptor β subunit. CD131 is a single-pass type I transmembrane protein, belongs to the cytokine receptor superfamily, and is shared by IL-3, IL-5, and GM-CSF receptors. The receptor-specific α subunits is mainly involved in ligand binding and the common β subunit, CD131, is important for transducing the signal initiated by binding of the ligands to respective receptors. | Additional information: Clone REA193 displays negligible binding to Fc receptors. | |
Immunogen | n/a |
Other Names | CSF2RB, AIC2B, Bc, CDw131, Csf2rb1, Csfgmrb, IL3R, IL3RB, Il3rb1, IL5RB |
Gene, Accession # | Gene ID: 12983 |
Catalog # | 130-103-076 |
Price | $59 |
Order / More Info | CD131, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Goodall, G. J. et al. (1993) A model for the interaction of the GM-CSF, IL-3 and IL-5 receptors with their ligands. Growth Factors 8 (2): 87-97. | Guthridge, M. A. et al. (1998) Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors. Stem Cells 16 (5): 301-313. |