CD61, Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD61, Mouse/Rat |
| Clone | REA1192 |
| Host Species | Recombinant Human |
| Reactive Species | mouse, rat |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD61 Antibody, anti-mouse/rat, PE, REAfinity™. Clone REA1192 recognizes a 110 kDa integrin β chain known as CD61 or integrin β3. Owing to multiple α/β subunit combinations, integrins form an array of heterodimeric receptors, each recognising a multitude of ligands. CD61, in association with either αv (CD51) or αIIb (CD41) integrin, binds to fibrinogen, fibronectin, von Willebrand factor, prothrombin, disintegrins, and thrombospondin. Due to binding to various extracellular matrix proteins and cellular receptors, integrins play a significant role in cell adhesion and cell movement. Furthermore, a pro-apoptotic function of CD61 has been suggested using a hepatocellular carcinoma (HCC) cell line and patient tissues. Expression of CD61 is found on platelets, B cell subsets, myeloid cells, mast cells, osteoclasts, endothelium, megakaryocytes, and smooth muscle cells. | Additional information: Clone REA1192 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | ITGB3, GP3A, INGRB3, GPIIIa, Integrin beta-3, Integrin β3 |
| Gene, Accession # | Gene ID: 16416 |
| Catalog # | 130-122-148 |
| Price | $71 |
| Order / More Info | CD61, Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Plow, E. F. et al. (2000) Ligand binding to integrins. J. Biol. Chem. 275: 21785-21788. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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