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Antigenic Specificity | TOM22, Human/Mouse |
Clone | REA1185 |
Host Species | Recombinant Human |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TOM22 Antibody, anti-human/mouse, APC, REAfinity™. Clone REA1185 recognizes the human and mouse mitochondrial import receptor subunit TOM22 homolog antigen, a single-pass membrane protein which is also known as translocase of outer membrane 22 kDa subunit homolog. TOM22 is a central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. It functions together with the peripheral receptor TOM20 as the transit peptide receptor and facilitates the movement of pre-proteins into the translocation pore. | Additional information: Clone REA1185 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | hTom22, 1C9-2, Tomm22 |
Gene, Accession # | Gene ID: 56993, 223696, 300075 |
Catalog # | 130-122-082 |
Price | $140 |
Order / More Info | TOM22, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Shiota, T. et al. (2011) In vivo protein-interaction mapping of a mitochondrial translocator protein Tom22 at work. Proc. Natl. Acad. Sci. U.S.A. 108 (37): 15179-15183. | Bellot, G. et al. (2007) TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax. Cell Death Differ. 14 (4): 785-794. | Yano, M. et al. (2000) Identification and functional analysis of human Tom22 for protein import into mitochondria. Mol. Cell. Biol. 20 (19): 7205-7213. |