CD49e, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD49e, Mouse |
| Clone | 5H10-27 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2aκ |
| Format | allophycocyanin (APC) conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD49e Antibody, anti-mouse, APC. The monoclonal antibody 5H10-27 recognizes mouse CD49e, also known as integrin α5, which interacts with integrin β1 (CD29) to form the heterodimer VLA-5, the fibronectin receptor. It is expressed on activated T cells, thymocytes, mast cells, and splenic B cells and plays a role in cell-surface mediated signaling and in adhesion. The 5H10-27 antibody has been shown to inhibit VLA-5 mediated functions and promote the stimulation of CD8+ cells in vitro. | |
| Immunogen | n/a |
| Other Names | ITGA5, FNRA, VLA5 |
| Gene, Accession # | Gene ID: 16402 |
| Catalog # | 130-103-383 |
| Price | $61 |
| Order / More Info | CD49e, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Rich, S. et al. (1996) Role of alpha 5 beta 1 integrin in TGF-beta 1-costimulated CD8+ T cell growth and apoptosis. J Immunol 157: 2916-2923. | Noto, K. et al. (1995) Identification and functional characterization of mouse CD29 with a mAb. Int. Immunol. 7: 835-842. | Hemler, M. E. et al. (1990) LA proteins in the integrin family: structures, functions, and their role on leukocytes. Annu. Rev. Immunol. 8: 365-400. | Yang, J. T. et al. (1996) Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins. Mol. Biol. Cell 7: 1737-1748. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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