Ly-49G2, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Ly-49G2, Mouse |
| Clone | REA1053 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | APC-Vio 770 conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ly-49G2 Antibody, anti-mouse, APC-Vio® 770, REAfinity™. Clone REA1053 recognizes Ly-49G2, which is a inhibitory receptor specific for class Ia MHC molecules. Ly-49G2 belongs to the Ly-49 multigene family, which consists of type II transmembrane homodimeric receptors. Inhibitory Ly-49 members such as Ly-49G2 contain immunoreceptor tyrosine-based inhibitory motif (ITIM) 3 in their cytoplasmic tail and transduce signal that prevents the NK cell cytolytic activity upon recognizing ligands such as H-2Ddk. Expression of Ly-49G2 is found on subsets of natural killer (NK) cells, NK-T cells, and on a population of memory CD8+ T cells (in C57BL/6 mice). | Additional information: Clone REA1053 displays negligible binding to Fc receptors |
| Immunogen | n/a |
| Other Names | Klra7, LGL-1, Ly49G.4, Ly-49G, Ly49g1, Ly-49G2 |
| Gene, Accession # | Gene ID: 16638 |
| Catalog # | 130-118-037 |
| Price | $141 |
| Order / More Info | Ly-49G2, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Silver, E. T. et al. (2002) Allelic variation in the ectodomain of the inhibitory Ly-49G2 receptor alters its specificity for allogeneic and xenogeneic ligands. J Immunol 169: 4752-4760. | Barao, I. et al. (2011) Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC. Blood 117: 7032-7041. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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