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Antigenic Specificity | β-Actin, Human |
Clone | REAL1032 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | allophycocyanin (APC) conjugate |
Size | 200 µL |
Concentration | n/a |
Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | β-Actin Antibody, anti-human, APC, REAdye_lease™. Clone REAL1032 is an antibody fragment derived from the full β-Actin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1032 recognizes β-Actin, which belongs to the actin family of highly conserved globular multi-functional proteins that play a role in various types of cell motility. They are able to form microfilaments and are found in all eukaryotic cells. β-Actin is a nonmuscle cytoskeletal actin and exists in most cell types as a component of the cytoskeleton and as a mediator of internal cell motility. Mutatations in this gene may be associated with diffuse large B- cell lymphoma. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
Immunogen | n/a |
Other Names | Beta-actin, ACTB |
Gene, Accession # | n/a |
Catalog # | 130-127-407 |
Price | $470 |
Order / More Info | β-Actin, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Lohr, J. G. et al. (2012) Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proc. Natl. Acad. Sci. U.S.A. 109 (10): 3879-3884. | Gunning, P. W. et al. (2015) The evolution of compositionally and functionally distinct actin filaments. J. Cell. Sci. 128 (11): 2009-2019. | Hanukoglu, I. et al. (1983) Complementary DNA sequence of a human cytoplasmic actin. Interspecies divergence of 3' non-coding regions. J. Mol. Biol. 163 (4): 673-678. |