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Antigenic Specificity | CD158e/k (KIR3DL1/DL2), Human |
Clone | REA970 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD158e/k (KIR3DL1/DL2) Antibody, anti-human, APC, REAfinity™. Clone REA970 recognizes the human CD158e (KIR3DL1) and CD158k (KIR3DL2) antigens, members of the killer immunoglobulin-like receptor (KIR) family which recognizes subsets of HLA alleles. The family of KIR contributes to the regulation of NK cell-mediated cytotoxicity. Expression is found mainly on CD56dimCD16+ natural killer (NK) cells but also on a subset of CD8+ T cells. They are monomeric receptors possessing high allelic polymorphism with either two or three Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be subdivided in inhibitory KIRs and activating KIRs. | Additional information: Clone REA970 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | KIR3DL1, KIR3DL2 |
Gene, Accession # | Gene ID: 3811 |
Catalog # | 130-116-282 |
Price | $140 |
Order / More Info | CD158e/k (KIR3DL1/DL2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Yawata, M. et al. (2002) Variation within the human killer cell immunoglobulin-like receptor (KIR) gene family. Crit. Rev. Immunol. 22 (5-6): 463-482. | Uhrberg, M. (2005) The KIR gene family: life in the fast lane of evolution. Eur. J. Immunol. 35 (1): 10-15. |