CD261, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD261, Human
CloneDJR1
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1κ
Formatphycoerythrin (PE) conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsFlow cytometry
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DescriptionCD261 Antibody, anti-human, PE. The DJR1 monoclonal antibody recognizes the human antigen CD261, which is also known as DR4 or TRAILR1. CD261 belongs to the TNF receptor family and is a receptor for TNFSF10/ trail. It promotes the activation of NF-κB and induces TRAIL-mediated apoptosis. CD261 is expressed on spleen, peripheral blood leukocytes, small intestine, and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells, and activated T cells. | | | | | | |
Immunogenn/a
Other NamesTNFRSF10A, APO2, DR4, TRAILR1
Gene, Accession #Gene ID: 8797
Catalog #130-109-030
Price$310
Order / More InfoCD261, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesChaudhary, P. M. et al. (1997) Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity 7 (6): 821-830. | Pan, G. et al. (1997) The receptor for the cytotoxic ligand TRAIL. Science 276 (5309): 111-113.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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