P2X7R, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | P2X7R, Mouse |
| Clone | REA875 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | P2X7R Antibody, anti-mouse, PE, REAfinity™. Clone REA875 recognizes the mouse P2X7R antigen, also known as P2RX7 or P2X7 (P2X purinoceptor 7), which is a receptor for ATP that acts as a ligand-gated ion channel. P2X7R is involved in different inflammatory, immune, neurologic, and musculoskeletal disorders and is able to modulate LPS-induced macrophage production of inflammatory mediators. P2X7R is found on cells of the immune system, e.g., mast cells, microglia, macrophages, T cells, and B cells, in uterine endometrium, retina, and in the central and peripheral nervous systems. | Additional information: Clone REA875 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | P2RX7, P2X7 |
| Gene, Accession # | Gene ID: 18439 |
| Catalog # | 130-114-329 |
| Price | $72 |
| Order / More Info | P2X7R, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Chessell, I. P. et al. (1998) Cloning and functional characterisation of the mouse P2X7 receptor. FEBS Lett. 439 (1-2): 26-30. | Kawano, A. et al. (2012) Involvement of P2X4 receptor in P2X7 receptor-dependent cell death of mouse macrophages. Biochem. Biophys. Res. Commun. 419 (2): 374-380. | Alves, L. A. et al. (2014) The P2X7 receptor: shifting from a low- to a high-conductance channel - an enigmatic phenomenon? Biochim. Biophys. Acta 1838 (10): 2578-2587. | Bartlett, R. et al. (2014) The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease. Pharmacol. Rev. 66 (3): 638-675. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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