NKp80, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | NKp80, Human |
| Clone | REA845 |
| Host Species | Recombinant Human |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1 |
| Format | VioBlue conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | NKp80 Antibody, anti-human, VioBlue®, REAfinity™. Clone REA845 recognizes the human NKp80 antigen, an 80 kDa homodimeric surface molecule belonging to the family of C-type lectin-like receptors. NKp80 is expressed on all human natural killer (NK) cells and on a small subset of effector memory CD8+ T cells. NKp80 stimulates NK cell cytotoxicity and cytokine release and appears to co-operate with other triggering receptors to induce optimal NK cell activation upon interaction with potential target cells. The ligand of NKp80 is activation-induced C-type lectin (AICL), also called CLEC2B. | Additional information: Clone REA845 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | KLRF1, CLEC5C |
| Gene, Accession # | Gene ID: 51348 |
| Catalog # | 130-112-785 |
| Price | $148 |
| Order / More Info | NKp80, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Kuttruff, S. et al. (2009) NKp80 defines and stimulates a reactive subset of CD8 T cells. Blood 113: 358-369. | Welte, S. et al. (2006) Mutual activation of natural killer cells and monocytes mediated by NKp80-AICL interaction. Nat Immunol 7: 1334-1342. | Vitale, M. et al. (2001) Identification of NKp80, a novel triggering molecule expressed by human NK cells. Eur. J. Immunol. 31: 233-242. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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