Collagen I, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCollagen I, Human
CloneREAL1355
Host SpeciesRecombinant Human
Reactive Specieshuman
Isotypen/a
Formatallophycocyanin (APC) conjugate
Size200 µL
Concentrationn/a
ApplicationsMICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence
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DescriptionCollagen I Antibody, anti-human, APC, REAdye_lease™. Clone REAL1355 is an antibody fragment derived from the full Collagen I antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1355 recognizes Collagen I also known as pro-alpha1(I) chain, a member of group I collagen (fibrillar forming collagen). Collagen I is encoded by the COL1A1 gene and forms the fibrils of tendon, dermis, cornea and bones. In bones the fibrils are mineralized with calcium hydroxyapatite. Mutations in the COL1A1 gene are associated with Osteogenesis,the Ehlers-Danlos syndrome and different types of cancers. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
Immunogenn/a
Other NamesCollagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
Gene, Accession #n/a
Catalog #130-130-612
Price$510
Order / More InfoCollagen I, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesMatthew, D. et al. (2009) COLLAGEN STRUCTURE AND STABILITY. Annu Rev. Biochem. 78: 929-958. | Ma, H. P. et al. (2019) Collagen 1A1 (COL1A1) Is a Reliable Biomarker and Putative Therapeutic Target for Hepatocellular Carcinogenesis and Metastasis. Cancers (Basel) 11 (6): 786.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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