CD103, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD103, Mouse |
| Clone | REA789 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD103 Antibody, anti-mouse, PE, REAfinity™. Clone REA789 recognizes the mouse CD103 antigen, a 175 kDa large, type I transmembrane glycoprotein also known as αE integrin. CD103 associates non-covalently with integrin β7 thereby forming the heterodimeric integrin αEβ7. It mediates cell-cell contact and is involved in homing processes by binding to its ligand e-cadherin. CD103 is expressed on >90% of intestinal intraepithelial lymphocytes (IEL), epithelial T cells, and regulatory T cells. Due to its differential expression on dendritic cells from peripheral tissues, it is useful in identifying dendritic cell subsets from intestinal lamina propria, lung, and dermis. | Additional information: Clone REA789 displays negligible binding to Fc receptors |
| Immunogen | n/a |
| Other Names | ITGAE, aM290, alpha-E1, alpha-M290, integrin alpha E |
| Gene, Accession # | Gene ID: 16407 |
| Catalog # | 130-111-607 |
| Price | $243 |
| Order / More Info | CD103, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Sung, S. S. et al. (2006) A major lung CD103 alphaE-beta7 integrin-positive epithelial dendritic cell population expressing Langerin and tight junction proteins. J Immunol 176 (9): 2161-2172. | Bogunovic, M. et al. (2009) Origin of the lamina propria dendritic cell network. Immunity 31 (3): 513-525. | Ginhoux, F. et al. (2007) Blood-derived dermal Langerin+ dendritic cells survey the skin in the steady state. J. Exp. Med. 204 (13): 3133-3146. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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