CD13, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD13, Human
CloneREAL312
Host SpeciesRecombinant Human
Reactive Specieshuman
Isotypen/a
Formatallophycocyanin (APC) conjugate
Size100 tests in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD13 Antibody, anti-human, APC, REAlease®. Clone REAL312 is an antibody fragment derived from the full CD13 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL312 recognizes the CD13 antigen, a type II transmembrane glycoprotein, which is also known as aminopeptidase N or gp150. CD13 is expressed on granulocytes, myeloid progenitors, endothelial cells, epithelial cells, and subset of granular lymphoid cells. It is also broadly expressed in other tissues such as kidney proximal tubules, intestine, and placenta. CD13 is an enzyme that is used as a biomarker to detect damage to the kidneys. It also serves as a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in CD13 appear to be a cause of various types of leukemia or lymphoma. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.
Immunogenn/a
Other NamesANPEP, APN, gp150, LAP1, p150, PEPN
Gene, Accession #n/a
Catalog #130-116-551
Price$385
Order / More InfoCD13, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesLook, A. T. et al. (1989) Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J. Clin. Invest. 83 (4): 1299-1307. | Yeager, C. L. et al. (1992) Human aminopeptidase N is a receptor for human coronavirus 229E. Nature 357 (6377): 420-422. | Favaloro, E. J. et al. (1993) CD13 (GP150; aminopeptidase-N): predominant functional activity in blood is localized to plasma and is not cell-surface associated. Exp. Hematol. 21 (13): 1695-1701.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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