MAP2, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Edit | |
|---|---|
| Antigenic Specificity | MAP2, Human/Mouse |
| Clone | REAL1048 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MAP2 Antibody, anti-human/mouse, PE, REAdye_lease™. Clone REAL1048 is an antibody fragment derived from the full MAP2 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1048 recognizes MAP2 (Microtubule-associated protein 2) and belongs to the microtubule-associated family. The proteins are involved in microtubules assembly, an essential step in neuritogenisis. MAP2 is known to stabilize microtubules growth by crosslinking each other and with intermediate filaments. MAP2 is suspected of interacting with tubulin and is mainly expressed in neurons. It has been reported, that it is also detected in different cancers including melanoma and breast cancer. Four isoforms of MAP2 have been characterized, MAP2A; MAP2B; MAP2C and MAP2D. MAP2D is expressed by glia cells. The MAP2 isoforms are thought to be involved in microtubule assembly. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
| Immunogen | n/a |
| Other Names | Microtubule-associated protein 2, MAP-2 |
| Gene, Accession # | n/a |
| Catalog # | 130-128-142 |
| Price | $460 |
| Order / More Info | MAP2, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Goedert, M. et al. (1991) Molecular characterization of microtubule-associated proteins tau and MAP2. Trends Neurosci. 14 (5): 193-199. | Soltani, M. H. et al. (2005) Microtubule-associated protein 2, a marker of neuronal differentiation, induces mitotic defects, inhibits growth of melanoma cells, and predicts metastatic potential of cutaneous melanoma. Am. J. Pathol. 166 (6): 1841-1850. | Dehmelt, L. et al. (2005) The MAP2/Tau family of microtubule-associated proteins. Genome Biol. 6 (1): 204-204. | Cabrera, J. R. et al. (2017) MAP2 Splicing is Altered in Huntington's Disease. Brain Pathol. 27 (2): 181-189. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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