KIR2D, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | KIR2D, Human |
| Clone | REA1042 |
| Host Species | Recombinant Human |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1 |
| Format | PE-Vio 770 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | KIR2D Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA1042 recognizes the killer immunoglobulin-like receptor (KIR) 2D subtype on human and non-human primate cells. It recognizes all KIRs bearing two extracellular Ig-like domains, and also both activating and inhibitory KIR isoforms (KIR2DS and KIR2DL, respectively). KIRs are expressed on CD56dimCD16+ natural killer (NK) cells and a subset of CD8+ T cells. KIRs contribute to the regulation of NK cell-mediated cytotoxicity. They are monomeric receptors possessing high allelic polymorphism with either two or three Ig-like extracellular domains (KIR2D or KIR3D, respectively). According to the length of their cytoplasmic tail, KIRs can be subdivided in long-tailed inhibitory KIRs (KIR2DL or KIR3DL) and short-tailed activating KIRs (KIR2DS or KIR3DS). | Additional information: Clone REA1042 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CD158A |
| Gene, Accession # | Gene ID: 3806, 3808, 3809, 3810, 3802, 3803, 3804, 3805, 57292, 100132285 |
| Catalog # | 130-117-483 |
| Price | $365 |
| Order / More Info | KIR2D, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Selvakumar, A. et al. (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol. Rev. 155: 183-196. | Hsu, K. et al. (2002) The killer cell immunoglobin-like (KIR) genomic region: gene-order, haplotypes and allelic polymorphism. Immunol. Rev. 190: 40-52. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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