Jak1, Human/Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Jak1, Human/Mouse/Rat |
| Clone | REA700 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Jak1 Antibody, anti-human/mouse/rat, PE, REAfinity™. Clone REA700 recognizes the human, mouse, and rat Jak1 antigen, also known as tyrosine-protein kinase JAK1 or janus kinase 1. Jak1 is a widely expressed membrane-associated phosphoprotein characterized by the presence of a second phosphotransferase-related domain immediately N terminal to the PTK domain. Jak1 is involved in the IFN-α/β/γ signal pathway and activates transcription factors of the STAT family by phosphorylating critical tyrosine regulatory sites. | Additional information: Clone REA700 displays negligible binding to Fc receptors |
| Immunogen | n/a |
| Other Names | Tyrosine-protein kinase JAK1, Janus kinase 1, JAK-1 |
| Gene, Accession # | Gene ID: 3716, 16451, 84598 |
| Catalog # | 130-110-607 |
| Price | $119 |
| Order / More Info | Jak1, Human/Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Wilks, A. F. et al. (1991) Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase. Mol. Cell. Biol. 11 (4): 2057-2065. | Williams, N. K. et al. (2009) Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase Domains. J. Mol. Biol. 387 (1): 219-232. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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