MHC Class II (I-Ab), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | MHC Class II (I-Ab), Mouse |
| Clone | REA528 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MHC Class II (I-Ab) Antibody, anti-mouse, PE, REAfinity™. Clone REA528 recognizes the mouse MHC class II alloantigen I-Ab of H-2b bearing mouse strains. It also cross-reacts with the H-2k and H-2u haplotypes, but reactivity to other haplotypes like, for example, d, f, g7, p, q, r, and s has not been observed. MHC class II is expressed on antigen-presenting cells, such as dendritic cells, monocytes, macrophages, B cells in lymphoid and non-lymphoid tissue, thymic epithelial cells, and on subsets of hematopoietic progenitor cells in the bone marrow. | Additional information: Clone REA528 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | MHC class II IAb |
| Gene, Accession # | Gene ID: 14961 |
| Catalog # | 130-117-392 |
| Price | $222 |
| Order / More Info | MHC Class II (I-Ab), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Cuenca, M. et al. (2016) Targeting of Ly9 (CD229) disrupts marginal zone and B1 B cell homeostasis and antibody responses. J Immunol 196: 726-737. | Gradehandt, G. et al. (1993) The I-Ab-restricted alloresponse of D10.G4.1 T cells is based on the recognition of an endogenous peptide. Immunology 78 (4): 592-599. | Tobita, T. et al. (2003) A role for the P1 anchor residue in the thermal stability of MHC class II molecule I-Ab. Immunol. Lett. 85 (1): 47-52. | Zhu, Y. et al. (2003) Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif. J. Mol. Biol. 326 (4): 1157-1174. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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