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Antigenic Specificity | LOX-1, Human |
Clone | REA1188 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | Vio Bright V423 conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LOX-1 Antibody, anti-human, Vio® Bright V423, REAfinity™. Clone REA1188 recognizes the human LOX-1 antigen, the lectin-like oxidized LDL receptor 1, which is also known as OLR1 and CLEC8A belonging to the C-type lectin superfamily. LOX-1 is found on on endothelial cells, macrophages, platelets, fibroblasts, and smooth muscle cells. It plays a role in endocytosis, phagocytosis, apoptosis, and inflammatory processes. | Additional information: Clone REA1188 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | CLEC8A, LOX1, hLOX-1, OLR1 |
Gene, Accession # | Gene ID: 4973 |
Catalog # | 130-131-072 |
Price | $498 |
Order / More Info | LOX-1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Sawamura, T. et al. (1997) An endothelial receptor for oxidized low-density lipoprotein. Nature 386 (6620): 73-77. | Draude, G. et al. (1999) The expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) on human vascular smooth muscle cells and monocytes and its down-regulation by lovastatin. Biochem. Pharmacol. 57 (4): 383-386. | Pirillo, A. et al. (2013) LOX-1, OxLDL, and atherosclerosis. Mediators Inflamm: . |