CD125 (IL-5Rα), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD125 (IL-5Rα), Human |
| Clone | REA705 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Vio Bright V423 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD125 (IL-5Rα) Antibody, anti-human, Vio® Bright V423, REAfinity™. Clone REA705 recognizes the human CD125 (IL-5Rα) antigen, a subunit of the heterodimeric interleukin 5 (IL-5) receptor which binds to IL-5. The human IL-5 receptor has an a subunit (IL-5Rα) and a b subunit (βC) that are able to activate the Janus kinases JAK1 and JAK2 and a signal transducer and activator of transcription (STAT5). CD125 is expressed on eosinophils and basophils. | Additional information: Clone REA705 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | IL-5RA, CDw125 |
| Gene, Accession # | Gene ID: 3568 |
| Catalog # | 130-130-611 |
| Price | $208 |
| Order / More Info | CD125 (IL-5Rα), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Blom, M. et al. (1994) Granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 greatly enhance the interaction of human eosinophils with opsonized particles by changing the affinity of complement receptor type 3. Blood 83 (10): 2978-2984. | Ogata, N. et al. (1998) JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are activated upon IL-5 stimulation. Blood 91 (7): 2264-2271. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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