CD228, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD228, Human |
| Clone | REA717 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD228 Antibody, anti-human, PE, REAfinity™. Clone REA717 recognizes the human CD228 antigen, a cell-surface sialoglycoprotein also known as MFI2 or melanotransferrin. CD228 is mainly found in human melanomas, but also in liver, epithelium, and in certain fetal tissues. It plays a role in iron cellular uptake. CD228 is internalized before being recycled back to the cell membrane and is also able to bind zinc. | Additional information: Clone REA717 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Melanotransferrin, MFI2, MAP97, MTF1 |
| Gene, Accession # | Gene ID: 4241 |
| Catalog # | 130-111-408 |
| Price | $110 |
| Order / More Info | CD228, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Baker, E. N. et al. (1992) Human melanotransferrin (p97) has only one functional iron-binding site. FEBS Lett. 298 (2-3): 215-218. | Kennard, M. L. et al. (1995) A novel iron uptake mechanism mediated by GPI-anchored human p97. EMBO J. 14 (17): 4178-4186. | Suryo Rahmanto, Y. et al. (2007) The melanoma tumor antigen, melanotransferrin (p97): a 25-year hallmark--from iron metabolism to tumorigenesis. Oncogene 26 (42): 6113-6124. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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