CD270 (HVEM), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

Search, find, compare suppliers for anti-CD270 (HVEM), Human antibody, protein, ELISA kits.

Edit 
Antigenic SpecificityCD270 (HVEM), Human
CloneREA247
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
FormatPE-Vio 770 conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsFlow cytometry
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionCD270 (HVEM) Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA247 recognizes CD270, which is also known as HVEM and derives its name based on the ability of types 1 and 2 herpesvirus gD to bind to it for entry into the cell. CD270 is a type 1 transmembrane protein with a predicted molecular weight of 30 kDa and is a member of the TNFR superfamily. CD270 transmits both activating and inhibitory signals for, e.g., interaction with receptors such as BTLA or CD160 attenuates TCR-mediated signaling, whereas interaction with receptor LIGHT allows co-stimulation of T and B cells. Expression of CD270 is widely distributed and is found on hematopoietic cells such as dendritic cells, Tregs, monocytes, neutrophils, NK cells, B cells, and T cells, as well as on non-hematopoietic cells. | Additional information: Clone REA247 displays negligible binding to Fc receptors. |
Immunogenn/a
Other NamesTNFRSF14, ATAR, HVEA, HVEM, LIGHTR, TR2
Gene, Accession #Gene ID: 8764
Catalog #130-101-600
Price$350
Order / More InfoCD270 (HVEM), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesWare, C. F. et al. (2009) Targeting the LIGHT-HVEM pathway. Adv. Exp. Med. Biol. 647: 146-155. | Pasero, C. et al. (2012) The HVEM network: new directions in targeting novel costimulatory/co-inhibitory molecules for cancer therapy. Curr. Opin. Pharmacol. 12 (4): 478-485.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies

© 1980 - 2024 Linscott's Directory, Linscott's USA. All rights reserved.