Dnmt3b, Human/Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-Dnmt3b, Human/Mouse/Rat antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Dnmt3b, Human/Mouse/Rat |
| Clone | REA565 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 tests in 300 µL |
| Concentration | 1:11 |
| Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Dnmt3b Antibody, anti-human/mouse/rat, APC, REAfinity™. Clone REA565 recognizes the Dnmt3b antigen, which is a DNA methyltransferase, that performs de novo DNA methylation during embryonic development. It may function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation and may play a role in controlling the differentiation of human ES cells and in the generation of iPS cells. Dnmt3 is expressed ubiquitously, at higher levels expressed in mouse and human embryonic stem (ES), in fetal liver, heart, kidney, and placenta. | Additional information: Clone RE565 displays negligible binding to Fc receptors. | | | | |
| Immunogen | n/a |
| Other Names | ICF, MmuIIIB, ICF1, M.HsaIIIB |
| Gene, Accession # | Gene ID: 1789, 444985 |
| Catalog # | 130-108-797 |
| Price | $142 |
| Order / More Info | Dnmt3b, Human/Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Yajun, L. et al. (2010) Interaction between DNMT3B and polycomb repression complexes and their role in histone modification. Cancer Res. 70: 4868-4868. | Wongtrakoongate, P. et al. (2014) DNMT3B inhibits the re-expression of genes associated with induced pluripotency. Exp. Cell Res. 321 (2): 231-239. | Niederwieser, C. et al. (2015) Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia. Leukemia 29 (3): 567-575. | Torroglosa, A. et al. (2014) Involvement of DNMT3B in the pathogenesis of Hirschsprung disease and its possible role as a regulator of neurogenesis in the human enteric nervous system. Genet. Med. 16 (9): 703-710. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies