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Antigenic Specificity | CD123, Human |
Clone | AC145 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2aκ |
Format | phycoerythrin (PE) conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD123 Antibody, anti-human, PE. CD123 is also known as interleukin 3 (IL-3) receptor α-chain and is the primary low-affinity subunit of the IL-3 receptor. CD123 associates with CD131, the common β-chain of the IL-3, IL-5, and GM-CSF receptor, to form the high-affinity IL-3 receptor. The IL-3 receptor is involved in cell signaling for cell growth and differentiation. In peripheral blood, the CD123 antigen is expressed at high levels only on plasmacytoid dendritic cells and basophilic granulocytes but at low levels also on monocytes, eosinophilic granulocytes, myeloid dendritic cells, and subsets of hematopoietic progenitor cells. |
Immunogen | n/a |
Other Names | IL3RA, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra, IL-3Rα |
Gene, Accession # | Gene ID: 3563 |
Catalog # | 130-113-326 |
Price | $315 |
Order / More Info | CD123, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | van Dongen, J. J. M. et al. (2012) EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. Leukemia 26 (9): 1908-1975. | Choi, K.-D. et al. (2011) Hematopoietic differentiation and production of mature myeloid cells from human pluripotent stem cells. Nat. Protoc. 6 (3): 296-313. |