CD273 (PD-L2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD273 (PD-L2), Human |
| Clone | MIH18 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1κ |
| Format | PE-Vio 770 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD273 (PD-L2) Antibody, anti-human, PE-Vio® 770. Clone MIH18 recognizes human CD273, also known as B7-DC and PD-L2. CD273 with an approximate molecular weight of 25 kDa is a type I transmembrane protein, belonging to the B7 family of protein ligands and to the Ig superfamily. CD273 is mainly expressed on dendritic cells (DCs) and activated macrophages. It has been shown to interact with programmed-death-receptor 1 (PD-1). Both a stimulatory and inhibitory role of CD273, in T cell activation has been proposed. |
| Immunogen | n/a |
| Other Names | PDCD1LG2, B7-DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2 |
| Gene, Accession # | Gene ID: 80380 |
| Catalog # | 130-120-724 |
| Price | $355 |
| Order / More Info | CD273 (PD-L2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Tseng, S. Y. et al. (2001) B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J. Exp. Med. 193: 839-846. | Pfistershammer, K. et al. (2006) No evidence for dualism in function and receptors: PD-L2/B7-DC is an inhibitory regulator of human T cell activation. Eur. J. Immunol. 36 (5): 1104-1113. | Greenwald, R. J. et al. (2005) The B7 family revisited. Annu. Rev. Immunol. 23: 515-548. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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