Neurofilament, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Neurofilament, Human/Mouse |
| Clone | REA1127 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | Vio R667 conjugate |
| Size | 600 µL |
| Concentration | 1:50 |
| Applications | Mass cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Neurofilament Antibody, anti-human/mouse, Vio® R667, REAfinity™. Clone REA1127 recognizes the 68 kDa component of the polypeptide subunit of human Neurofilament. Under certain conditions, an additional 200 kDa band could be detected. It is not confirmed, if this is in fact a multimer of the 68 kDa protein. | Neurofilament belongs to the intermediate filament family. Neurofilament is a major component of the neuronal cytoskeleton and a useful marker for distinguishing neurons (which are positive for Neurofilament) from glia. It is found in several neural, neuroendocrine, and endocrine tumors, but also in carcinomas of skin and lung and paragangliomas and adrenal and extra-adrenal pheochromocytomas. REA1127 does not recognize GFAP, keratin, vimentin and desmin or small cell lung carcinoma. | Additional information: Clone REA1127 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | Gene ID: 4747 |
| Catalog # | 130-131-154 |
| Price | $644 |
| Order / More Info | Neurofilament, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | van Muijen, G. N. et al. (1984) Cytokeratin and neurofilament in lung carcinomas. Am. J. Pathol. 116 (3): 363-369. | Szaro, B. G. and Strong, M. J. (2010) Post-transcriptional control of neurofilaments: New roles in development, regeneration and neurodegenerative disease. Trends Neurosci. 33 (1): 27-37. | Wang, H. et al. (2012) Neurofilament proteins in axonal regeneration and neurodegenerative diseases. Neural Regen. Res. 7 (8): 620-626. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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