CD35, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD35, Human |
| Clone | E11 |
| Host Species | Mouse |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1κ |
| Format | biotin conjugate |
| Size | 30 tests in 300 µL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD35 Antibody, anti-human, Biotin. The monoclonal antibody E11 recognizes the human cell surface protein CD35, the C3b/C4b receptor, also known as CR1 or complement receptor type I. Four CD35 allotypes with different molecular weights are known; 190, 220, 250, and 280 kDa. CD35 is expressed on hematopoietic cells such as granulocytes, monocytes, B cells, subsets of natural killer (NK) and T cells, erythrocytes, and follicular dendritic cells (DCs). Known functions of CD35 include transport of C3 complexes on erythrocytes, complement activation, phagocytosis, and inhibition of the activation-induced proliferation of T and B cells. |
| Immunogen | n/a |
| Other Names | CR1, C3BR, C4BR, KN, C3b/C4b-R |
| Gene, Accession # | Gene ID: 1378 |
| Catalog # | 130-101-624 |
| Price | $99 |
| Order / More Info | CD35, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Reilly, B. et al. (2010) Human peripheral CD4+ T-cells expressing complement receptor 1 (CR1, CD35). J Immunol 184 (1 Supplement): 138.3. | Reynes, M. et al. (1985) Human follicular dendritic cells express CR1, CR2, and CR3 complement receptor antigens. J Immunol 135: 2687-2694. | Klickstein, L. B. et al. (1988) Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis. J. Exp. Med. 168: 1699-1717. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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