TCR Vβ3, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityTCR Vβ3, Mouse
CloneREA646
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
FormatPE-Vio 770 conjugate
Size30 µg in 1 mL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionTCR Vβ3 Antibody, anti-mouse, PE-Vio® 770, REAfinity™. Clone REA646 recognizes the mouse V beta 3 T cell receptor (TCR Vβ3). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ3 is a variant of the TCR β chain and is expressed on T cells having the a, b, and c haplotype of the TCR β gene complex. | Additional information: Clone REA646 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesTCR Vb3, Gm2426, Tcrb-V16
Gene, Accession #Gene ID: 100039790
Catalog #130-109-852
Price$167
Order / More InfoTCR Vβ3, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesLee, J. S. et al. (2006) Antigen-specific expansion of TCR Vbeta3+ CD4+ T cells in the early stage of collagen-induced arthritis and its arthritogenic role in DBA/1J mice. J. Clin. Immunol. 26 (3): 204-212. | Fairchild, S. et al. (1992) Tcrb-V3+ T-cell deletion and a new mouse mammary tumor provirus, Mtv-44. Immunogenetics 36 (3): 189-194. | Tomonari, K. et al. (1992) Tcrb-V3+ T-cell deletion and a mouse mammary tumor provirus, Mtv-27. Immunogenetics 36 (5): 302-305.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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