PEAR1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityPEAR1, Human
CloneREA790
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatallophycocyanin (APC) conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionPEAR1 Antibody, anti-human, APC, REAfinity™. Clone REA790 recognizes the human platelet endothelial aggregation receptor 1 (PEAR1) antigen, a type I transmembrane protein also known as MEGF12. PEAR1, an EGF-containing receptor and member of the MEGF family, is found in various tissues. High levels of PEAR1 are found in platelets and endothelial cells, it is weakly expressed in peripheral blood leukocytes and macrophages. PEAR1 becomes activated by platelet contact and is involved in agonist-induced platelet aggregation. | Additional information: Clone REA790 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesMEGF12
Gene, Accession #Gene ID: 375033
Catalog #130-111-690
Price$142
Order / More InfoPEAR1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesNanda, N. et al. (2005) Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation. J. Biol. Chem. 280 (26): 24680-24689. | Nanda, N. et al. (2006) Novel targets for antithrombotic drug discovery. Blood Cells Mol. Dis. 36 (2): 228-231. | Herrera-Galeano, J. E. et al. (2008) A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability. Arterioscler. Thromb. Vasc. Biol. 28 (8): 1484-1490.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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